Gastro-esophageal reflux disease (GERD) has become prevalent in the modern lifestyle of people. GERD is a chronic digestive disorder, which is caused by the backflow of gastric contents into the esophagus, due to weakened lower esophageal sphincter (LES). One of the primary symptoms of GERD is heartburn, which occurs to 7% U.S. population on a daily basis. GERD has spread over the globe rapidly over the past decade and its prevalence is account to be 15-25%. GERD drastically affects the quality of life and may develop into esophageal cancer. There are several treatments available in the market including lifestyle modifications, medication, devices or endoscopic procedures & surgery. The death of treatment option is what drives the GERD market.